Vaccinations are second only to clean water in terms of their benefit to public health. However, challenges remain in developing highly efficacious, long lasting, and low reactogenicity vaccines. No vaccine platform is perfect, and compromises often need to be made in finding a perfect match between efficacy against a pathogen and the safety profile. Once a formulation that delivers the necessary balance is achieved, there is still the need to ensure the production process can be scaled for high throughput manufacturing with replicable quality and yield. This presentation will provide an overview of the more recently available vaccine platforms developed by Sanofi, as well as those to come soon and give insight to future technologies under investigation.